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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ST8SIA5
All Species:
23.64
Human Site:
S258
Identified Species:
57.78
UniProt:
O15466
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15466
NP_037437.2
376
43895
S258
N
T
R
N
T
D
V
S
I
R
V
K
Y
V
L
Chimpanzee
Pan troglodytes
P61646
376
43903
S258
N
T
R
N
T
D
V
S
I
R
V
K
Y
V
L
Rhesus Macaque
Macaca mulatta
NP_001077419
376
43875
S258
N
T
R
N
T
D
V
S
I
R
V
K
Y
V
L
Dog
Lupus familis
XP_544243
331
38123
K221
F
K
V
Y
S
T
L
K
E
S
N
A
R
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
P70126
412
47739
S294
N
V
R
N
T
L
V
S
F
R
V
K
Y
M
L
Rat
Rattus norvegicus
Q07977
375
42381
A257
E
R
V
E
W
V
N
A
L
I
L
K
H
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506293
375
43779
S258
N
T
R
N
T
D
V
S
I
R
V
K
Y
V
L
Chicken
Gallus gallus
Q11200
342
39522
Y232
T
G
T
I
N
F
T
Y
V
P
V
P
R
K
I
Frog
Xenopus laevis
Q6ZXA0
359
40793
T249
E
D
F
G
T
N
Q
T
V
L
F
A
N
P
N
Zebra Danio
Brachydanio rerio
XP_001336062
374
43321
S258
N
T
R
N
T
D
V
S
F
R
V
K
Y
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.4
37.2
N.A.
77.9
28.1
N.A.
90.9
24.4
39.6
72.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.7
52.3
N.A.
84.4
48.4
N.A.
97.3
39.8
54.5
88.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
73.3
6.6
N.A.
100
6.6
6.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
80
40
N.A.
100
20
26.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
20
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
0
10
0
0
10
0
0
20
0
10
0
0
0
0
% F
% Gly:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
40
10
0
0
0
0
10
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
0
70
0
10
10
% K
% Leu:
0
0
0
0
0
10
10
0
10
10
10
0
0
0
60
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% M
% Asn:
60
0
0
60
10
10
10
0
0
0
10
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
10
60
0
0
0
0
0
0
60
0
0
20
0
0
% R
% Ser:
0
0
0
0
10
0
0
60
0
10
0
0
0
0
0
% S
% Thr:
10
50
10
0
70
10
10
10
0
0
0
0
0
0
0
% T
% Val:
0
10
20
0
0
10
60
0
20
0
70
0
0
40
10
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
10
0
0
0
0
60
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _